Season
Episode
- Episode 1: Michael Strahan, Sebastian Maniscalco, Leon Bridges
- Episode 2: Keith Urban, Margaret Qualley
- Episode 3: Shaquille O'Neal, Chloë Sevigny, MJ Lenderman
- Episode 4: Cate Blanchett, Marcello Hernández, Nick Griffin
- Episode 5: Kate McKinnon, Kit Connor and Rachel Zegler, Jelly Roll, Jelly Roll and mgk
- Episode 6: Sarah Paulson, Jack Antonoff, Teddy Swims
- Episode 7: Luke Bryan, Colin Kaepernick
- Episode 8: Chris Martin, Chase Stokes, Sabrina Carpenter
- Episode 9: Hoda Kotb, Henrik Lundqvist, Gabriel LaBelle, Vampire Weekend
- Episode 10: Chris Pine, Nicholas Braun, Mary Mack
- Episode 11: Pharrell Williams, Rachel Sennott, FINNEAS
- Episode 12: Jordan Peele, Madelyn Cline, Kane Brown
- Episode 13: Samuel L. Jackson, Justin Hartley, Tommy Richman
- Episode 14: Tom Holland, Bridget Everett, Damiano David
- Episode 15: Megan Thee Stallion, Billy Crystal, Julian Casablancas + The Voidz
- Episode 16: Sacha Baron Cohen, Brett Goldstein, Ian Lara
- Episode 17: Reba McEntire, Lauren Lapkus, A.J. & Big Justice, The Rizzler, Sevdaliza, Yseult
- Episode 18: Olivia Rodrigo, Keri Russell, Andrea Bocelli, Lauren Daigle
- Episode 19: Salma Hayek Pinault, David Chang, Kelsea Ballerini
- Episode 20: Anthony Mackie, Sarah Sherman, Shin Lim
- Episode 21: Kevin Kline, Lester Holt, Maddie Wiener
- Episode 22: Whoopi Goldberg, Rosie Perez, Bailey Zimmerman
- Episode 23: Saoirse Ronan, Carmelo Anthony, David Gilmour
- Episode 24: Dwayne Johnson, Rebecca Ferguson, Ella Langley, Riley Green
- Episode 25: Jeff Goldblum, Luke Grimes, Lacey Chabert
- Episode 26: Cynthia Erivo, Martha Stewart, Travis Fimmel, Emma Willmann
- Episode 27: Ariana Grande, Michael Bublé
- Episode 28: Jon Hamm, Lindsay Lohan, Pharrell
- Episode 29: Cher, Zoey Deutch, Gwen Stefani
- Episode 30: Keke Palmer, William Zabka, Mickey Drexler, Rauw Alejandro
- Episode 31: Richard Gere, Bowen Yang, Jin
- Episode 32: Gwyneth Paltrow, DJ Khaled, TV On the Radio
- Episode 33: Kaley Cuoco, Rickie Fowler, Xander Schauffele, Matt Fitzpatrick, Cameron Young, GloRilla
- Episode 34: Anthony Anderson, Jodie Turner-Smith, D.J. Demers
- Episode 35: Ben Stiller, Katie Holmes, Heavy MakeUp
- Episode 36: Jerry Seinfeld, Cody Rhodes, Billy Strings
- Episode 37: Lin-Manuel Miranda, Shailene Woodley, Nathy Peluso
- Episode 38: Amy Adams, Fortune Feimster, Dan + Shay
- Episode 39: Ice-T, Isabella Rossellini, Body Count
- Episode 40: Angelina Jolie, Sebastian Stan, Andrew Ridgeley, Laura Peek
- Episode 41: Keira Knightley, Christian Slater, Dean Edwards
- Episode 42: John Mulaney, Linda Cardellini, Julien Baker, Torres
- Episode 43: Ray Romano, Rose
- Episode 44: Lisa Kudrow, Elle Fanning, Jack Huston, Kamasi Washington
- Episode 45: Fred Armisen, Lily-Rose Depp, André 3000
- Episode 46: Michael Fassbender, Dustin Nickerson
- Episode 47: Nate Bargatze/Jessica Williams/Nicole Avant/Darlene Love
- Episode 48: Martin Short, Chloe Fineman, The Roots
- Episode 49: Joe Manganiello, Charli D'Amelio, Busta Rhymes
- Episode 50: Pamela Anderson, Andrew Rannells, Lil Baby
- Episode 51: Jamie Lee Curtis, Mikey Madison, Michael Shannon & Jason Nanducy
- Episode 52: Willie Geist, Pete Lee
- Episode 53: Bad Bunny, Karla Sofia Gascon, Linus Sebastian
- Episode 54: Jeff Daniels, Gabriel Basso, The Marías
- Episode 55: Savannah Guthrie & Craig Melvin, Sam Heughan, Lucy Dacus
- Episode 56: Kenny Chesney, Brooke Shields, Mekki Leeper, Dusty Slay
- Episode 57: Colin Jost, Stereo MC's
- Episode 58: Sarah Silverman, Bobby Cannavale, Lola Young
- Episode 59: Lucy Liu, Questlove, Debra DiGiovanni
The Tonight Show Starring Jimmy Fallon Season 12 Jamie Lee Curtis, Mikey Madison, Michael Shannon & Jason Nanducy
After Jay Leno's second retirement from the program, Jimmy Fallon stepped in as his permanent replacement. After 42 years in Los Angeles the program was brought back to New York.
